The Blocks database--a system for protein classification
نویسندگان
چکیده
منابع مشابه
The Blocks database--a system for protein classification
The Blocks Database contains multiple alignments of conserved regions in protein families. The database can be searched by e-mail and World Wide Web(WWW) servers (http://blocks.fhcrc.org/help) to classify protein and nucleotide sequences.
متن کاملProtein family classification based on searching a database of blocks.
The most highly conserved regions of proteins can be represented as "blocks" of locally aligned sequence segments. Previously, an automated system was introduced to generate a database of blocks that is searched for local similarities using a sequence query. Here, we describe a method for searching this database that can also reveal significant global similarities. Local and global alignments a...
متن کاملGENERATING FUZZY RULES FOR PROTEIN CLASSIFICATION
This paper considers the generation of some interpretable fuzzy rules for assigning an amino acid sequence into the appropriate protein superfamily. Since the main objective of this classifier is the interpretability of rules, we have used the distribution of amino acids in the sequences of proteins as features. These features are the occurrence probabilities of six exchange groups in the seque...
متن کاملIncreased coverage of protein families with the Blocks Database servers
The Blocks Database WWW (http://blocks.fhcrc.org ) and Email ([email protected] ) servers provide tools to search DNA and protein queries against the Blocks+ Database of multiple alignments, which represent conserved protein regions. Blocks+ nearly doubles the number of protein families included in the database by adding families from the Pfam-A, ProDom and Domo databases to those from PR...
متن کاملCDD: a Conserved Domain Database for protein classification
The Conserved Domain Database (CDD) is the protein classification component of NCBI's Entrez query and retrieval system. CDD is linked to other Entrez databases such as Proteins, Taxonomy and PubMed, and can be accessed at http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=cdd. CD-Search, which is available at http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi, is a fast, interactive tool to ide...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1996
ISSN: 1362-4962
DOI: 10.1093/nar/24.1.197